Overview

  • Product nameAnti-MPP1 antibodySee all MPP1 primary antibodies ...
  • Description
    Rabbit polyclonal to MPP1
  • Tested applicationsWB, IHC-P more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rabbit, Cow
  • Immunogen

    Recombinant fragment containing a sequence corresponding to a region within amino acids 1-274 of Human MPP1 (NP_002427).

  • Positive control
    • HepG2 whole cell lysate, H3347 xenograft; A431, H1299, HeLa, Molt-4 and Raji lysates

Properties

  • FormLiquid
  • Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab96253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB 1/500 - 1/3000. Predicted molecular weight: 52 kDa.
IHC-P 1/100 - 1/500.

Target

  • FunctionEssential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 1 PDZ (DHR) domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Extensively palmitoylated.
  • Cellular localizationMembrane. Cell projection > stereocilium. Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non-myelin-forming Schwann cells.
  • Target information above from: UniProt accession Q00013 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • 55 kDa erythrocyte membrane protein antibody
    • AAG 12 antibody
    • AAG12 antibody
    • Aging associated gene 12 antibody
    • DXS552 antibody
    • DXS552E antibody
    • EM55_HUMAN antibody
    • EMP 55 antibody
    • EMP55 antibody
    • Erythrocyte membrane protein p55 antibody
    • Membrane protein antibody
    • Membrane protein palmitoylated 1 55kDa antibody
    • Membrane protein palmitoylated 1 antibody
    • Membrane protein, palmitoylated 1, 55kDa antibody
    • Migration related gene 1 antibody
    • MPP 1 antibody
    • MPP1 antibody
    • MRG 1 antibody
    • MRG1 antibody
    • OTTHUMP00000026054 antibody
    • OTTHUMP00000196176 antibody
    • p55 antibody
    • palmitoylated 1 antibody
    • Palmitoylated erythrocyte membrane protein antibody
    • Palmitoylated membrane protein 1 antibody
    • PEMP antibody
    see all

Anti-MPP1 antibody images

  • Anti-MPP1 antibody (ab96253) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 52 kDa
  • Immunohistochemical analysis of paraffin-embedded H3347 xenograft, using ab96253 antibody at 1/100 dilution.

References for Anti-MPP1 antibody (ab96253)

ab96253 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"