Anti-MPP1 antibody (ab96253)

Overview

• Product nameAnti-MPP1 antibodySee all MPP1 primary antibodies ...
• Description
  Rabbit polyclonal to MPP1
• Tested applicationsWB, IHC-P more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rabbit, Cow
• Immunogen

  Recombinant fragment containing a sequence corresponding to a region within amino acids 1-274 of Human MPP1 (NP_002427).

• Positive controlHepG2 whole cell lysate, H3347 xenograft; A431, H1299, HeLa, Molt-4 and Raji lysates

Properties

• FormLiquid
• Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
  Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Adapters
  • Transmembrane

  • Cardiovascular
  • Blood
  • Erythrocytes

Applications

Target

• FunctionEssential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
• Tissue specificityUbiquitous.
• Sequence similaritiesBelongs to the MAGUK family.
  Contains 1 guanylate kinase-like domain.
  Contains 1 PDZ (DHR) domain.
  Contains 1 SH3 domain.
• Post-translational
  modificationsExtensively palmitoylated.
• Cellular localizationMembrane. Cell projection > stereocilium. Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non-myelin-forming Schwann cells.

Target information above from: UniProt accession Q00013 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 510998 Cow
  • Entrez Gene: 4354 Human
  • Entrez Gene: 17524 Mouse
  • Entrez Gene: 100328768 Rabbit
  • Omim: 305360 Human
  • SwissProt: Q17QN6 Cow
  • SwissProt: Q00013 Human
  • SwissProt: P70290 Mouse

  • Unigene: 496984 Human
  • Unigene: 391267 Mouse

  see all

• Alternative names
  55 kDa erythrocyte membrane protein antibodyAAG 12 antibodyAAG12 antibody

  Aging associated gene 12 antibodyDXS552 antibodyDXS552E antibodyEM55_HUMAN antibodyEMP 55 antibodyEMP55 antibodyErythrocyte membrane protein p55 antibodyMembrane protein antibodyMembrane protein palmitoylated 1 55kDa antibodyMembrane protein palmitoylated 1 antibodyMembrane protein, palmitoylated 1, 55kDa antibodyMigration related gene 1 antibodyMPP 1 antibodyMPP1 antibodyMRG 1 antibodyMRG1 antibodyOTTHUMP00000026054 antibodyOTTHUMP00000196176 antibodyp55 antibodypalmitoylated 1 antibodyPalmitoylated erythrocyte membrane protein antibodyPalmitoylated membrane protein 1 antibodyPEMP antibody

  see all

Anti-MPP1 antibody images

• 

  Western blot - MPP1 antibody (ab96253)
  Anti-MPP1 antibody (ab96253) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
  
  Predicted band size : 52 kDa
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MPP1 antibody (ab96253)
  Immunohistochemical analysis of paraffin-embedded H3347 xenograft, using ab96253 antibody at 1/100 dilution.