Anti-MPZL antibody (ab221364)
Key features and details
- Rabbit polyclonal to MPZL
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MPZL antibody
See all MPZL primary antibodies -
Description
Rabbit polyclonal to MPZL -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment corresponding to Human MPZL aa 150 to the C-terminus.
Database link: O95297 -
Positive control
- HaCaT cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab221364 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100. |
Notes |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. Fixation/Permeabilization: PFA/Triton X-100. |
Target
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Relevance
Cell surface receptor, which is involved in signal transduction processes. Is a major receptor for concanavalin A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine protein kinases. Isoform 3 seems to block tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, unlike isoforms 2 and 3, may be involved in regulation of integrin mediated cell motility. -
Cellular localization
Membrane; single pass type I membrane protein (Potential) -
Database links
- Entrez Gene: 539387 Cow
- Entrez Gene: 9019 Human
- Entrez Gene: 68481 Mouse
- Entrez Gene: 360871 Rat
- GenBank: BC007881 Human
- Omim: 604376 Human
- SwissProt: Q32PI9 Cow
- SwissProt: O95297 Human
see all -
Alternative names
- immunoglobulin family transmembrane protein antibody
- MPZL1 antibody
- MPZL1b antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab221364 has not yet been referenced specifically in any publications.