|
|
|
|
|
Product Name
|
S100A9 antibody [0.N.390A]
|
| |
See all S100A9 antibodies (10)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Mouse monoclonal [0.N.390A] to S100A9
|
|
Immunogen
|
Affinity purified monocyte membrane preparation (Human).
|
|
Reacts with
(species key)
|
Hu, Ms, Rat, Bb, Cat, Dog, Gpig, Mk, Pig
|
|
Tested applications
(see key)
|
IHC-P
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
IHC-P: Use at a concentration of 1 - 2 µg/ml for 30 min at room temperature. Perform Antigen retrieval by digesting sections with trypsin at 1mg/ml PBS for 10 min at 37°C.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
Human Tonsil, lymph node or spleen.
|
|
Cellular localization
|
Cytoplasm; Nucleus (not nucleolus)
|
|
Research areas
|
Cancer >> Tumor biomarkers >> Other
Cancer >> Drug resistance >> MRP-related proteins
Cell Biology >> Cell Cycle >> Cell differentiation
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calcium Binding Proteins
Immunology >> Innate Immunity >> Macrophage / Inflamm.
|
|
Relevance
|
S100A9 is a member of the S100 family of proteins. S100A9, together with S100A8 forms a heterodimeric protein complex, Calprotectin, which is a major calcium- and zinc-binding protein in the cytosol of neutrophils, monocytes, and keratinocytes. Complexes of S100A8 and S100A9 are the physiologically relevant forms of these proteins.
S100A9 may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.
Its expression and potential cytokine-like function in inflammation and in cancer suggest that S100A8/A9 may play a key role in inflammation-associated cancer.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Mouse
|
|
Clonality
|
Monoclonal
|
|
Clone number
|
0.N.390A
|
|
Isotype
|
IgG1
|
|
Purity
|
Protein G purified
|
|
Storage buffer
|
Preservative: 0.09% Sodium Azide
Constituents: 0.2% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
|
|
Form
|
Liquid
|
|
Concentration
|
0.200 mg/ml
|
|
Storage instructions
|
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this S100A9 antibody [0.N.390A] is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to S100A9
|
| |
S100A9 antibody [0.N.390A] - more information
|
Customer reviews (feedback) regarding S100A9 antibody [0.N.390A] |
Customer FAQs regarding S100A9 antibody [0.N.390A] |
Protocols for S100A9 antibody [0.N.390A] |
Price and availability of products related to S100A9 antibody [0.N.390A] |
| |
S100A9 antibody [0.N.390A] - related products:
|
|
|
| |
S100A9 antibody [0.N.390A] - other tools:
|
Contact Abcam with a Technical Enquiry about S100A9 antibody [0.N.390A] |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
