You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Related products

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »
 

Anti-MRP4 antibody [M4I-10] (ab15602)

CodeSizePriceAbpointsAvailability
    
Add to basket
 
  • -
  •   
  •   
  •   
  •  
  •   
  •   
Updating...

Overview

Product name

Anti-MRP4 antibody [M4I-10]
See all MRP4 products (7) ...

Description

Rat monoclonal [M4I-10] to MRP4

Tested applications

WB, IHC-Fr, ICCmore details

Cross reactivity

Reacts with

Mouse, Human

Immunogen

This antibody was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the human MRP4 protein corresponding to amino acids 372-431.

Positive control

Kidney tissue

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: 0.7% BSA, Tissue culture supernatant

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

M4I-10

Isotype

IgG2a

Research areas

Cancer >> Drug resistance >> MRP-related proteins
Signal Transduction >> Metabolism >> Drug metabolism
Signal Transduction >> Metabolism >> Plasma Membrane >> Channels
Signal Transduction >> Metabolism >> Plasma Membrane >> ATPases

Applications

Show applications key

Our Abpromise guarantee covers the use of ab15602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

May be an organic anion pump relevant to cellular detoxification.

Tissue specificity

Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.

Sequence similarities

Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains.

Cellular localization

Membrane.

Target information above from: UniProt accessionO15439 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • ABCC 4 antibody
  • ABCC4 antibody
  • ATP binding cassette sub family C (CFTR/MRP) member 4 antibody
  • ATP binding cassette sub family C member 4 antibody
  • ATP binding cassette subfamily C member 4 antibody
  • ATP-binding cassette sub-family C member 4 antibody
  • bA464I2.1 (ATP binding cassette, sub-family C (CFTR/MRP) member 4) antibody
  • bA464I2.1 antibody
  • Canalicular multispecific organic anion transporter ABC superfamily antibody
  • canalicular multispecific organic anion transporter antibody
  • EST170205 antibody
  • MOAT B antibody
  • MOAT-B antibody
  • MOATB antibody
  • MRP 4 antibody
  • MRP cMOAT related ABC transporter antibody
  • MRP/cMOAT related ABC transporter antibody
  • MRP/cMOAT-related ABC transporter antibody
  • MRP4_HUMAN antibody
  • Multi specific organic anion transporter B antibody
  • Multi-specific organic anion transporter B antibody
  • Multidrug resistance associated protein 4 antibody
  • Multidrug resistance-associated protein 4 antibody
  • Multispecific organic anion tranporter B antibody
  • OTTHUMP00000018560 antibody
see all

Database links

References for Anti-MRP4 antibody [M4I-10] (ab15602)

This product has been referenced in:

  • Wijesuriya HCet al. ABC efflux transporters in brain vasculature of Alzheimer's subjects. Brain Res 1358:228-38 (2010). IHC-Fr; Human.Read more (PubMed: 20727860) »
  • Ose Aet al. Limited brain distribution of [3R,4R,5S]-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate phosphate (Ro 64-0802), a pharmacologically active form of oseltamivir, by active efflux across the blood-brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4). Drug Metab Dispos 37:315-21 (2009).Read more (PubMed: 19029202) »

See all 8 publications for this product

Publishing research using ab15602? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"