Anti-MRPL41 antibody (ab121922)

Overview

• Product nameAnti-MRPL41 antibodySee all MRPL41 primary antibodies ...
• Description
  Rabbit polyclonal to MRPL41
• Tested applicationsIHC-P more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  antigen sequence: GADRMSKWTS KRGPRSFRGR KGRGAKGIGF LTSGWRFVQI KEMVPEFVVP DLTGFKL, corresponding to amino acids 14-70 of Human MRPL41 (Q8IXM3).

  Run BLAST with Run BLAST with
• Positive controlHuman liver tissue.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferpH: 7.20
  Preservative: 0.02% Sodium azide
  Constituents: 59% PBS, 40% Glycerol
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Mitochondria

  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • Translation
  • Ribosome

  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • Translation
  • Mito. Translation

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Cell Cycle Inhibitors
  • Cip/Kip

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Cell Cycle Inhibitors
  • p53

  • Cell Biology
  • Cell Cycle
  • Cell Cycle Inhibitors
  • Cip / Kip

  • Cell Biology
  • Cell Cycle
  • Cell Cycle Inhibitors
  • p53

  • Cell Biology
  • Apoptosis
  • Intracellular
  • p53 Pathway

Applications

Target

• FunctionComponent of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.
• Tissue specificityPresent in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level).
• Sequence similaritiesBelongs to the ribosomal protein L41 family.
• Cellular localizationMitochondrion.

Target information above from: UniProt accession Q8IXM3 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 64975 Human
  • Omim: 611846 Human
  • SwissProt: Q8IXM3 Human
  • Unigene: 44017 Human

• Alternative names
  39S ribosomal protein L27 homolog antibody39S ribosomal protein L41 antibody39S ribosomal protein L41 mitochondrial antibody

  Bcl-2-interacting mitochondrial ribosomal protein L41 antibodyBMRP antibodyCell proliferation-inducing gene 3 protein antibodyL41mt antibodymitochondrial antibodyMitochondrial ribosomal protein L41 antibodyMRP L27 antibodyMRP-L27 homolog antibodyMRP-L41 antibodyMRPL27 antibodymRpL41 antibodyPIG3 antibodyProliferation inducing gene 3 antibodyRM41_HUMAN antibodyRPML27 antibody

  see all

Anti-MRPL41 antibody images

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPL41 antibody (ab121922)
  ab121922 at 1/20 dilution staining MRPL41 in paraffin-embedded Human liver tissue by Immunohistochemistry.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-MRPL41 antibody(ab121922)
  Immunohistochemical staining of Human rectum shows strong positivity in glandular cells using ab121922