Anti-MTMR6 antibody (ab69875)
Key features and details
- Mouse polyclonal to MTMR6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MTMR6 antibody
See all MTMR6 primary antibodies -
Description
Mouse polyclonal to MTMR6 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human MTMR6. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- MTMR6 transfected 293T cell lysate and human kidney tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab69875 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa). |
Target
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Function
Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells. -
Tissue specificity
Expressed in CD4+ T-cells. -
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Contains 1 myotubularin phosphatase domain. -
Cellular localization
Nucleus envelope. - Information by UniProt
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Database links
- Entrez Gene: 9107 Human
- Omim: 603561 Human
- SwissProt: Q9Y217 Human
- Unigene: 643702 Human
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Alternative names
- 4022440C11Rik antibody
- AI428804 antibody
- AU041072 antibody
see all
Images
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Anti-MTMR6 antibody (ab69875) at 1/500 dilution + human kidney tissue lysate at 50 µg
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 72 kDa
Observed band size: 72 kDa -
All lanes : Anti-MTMR6 antibody (ab69875) at 1/500 dilution
Lane 1 : MTMR6 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 72 kDa
Observed band size: 72 kDa
Datasheets and documents
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Datasheet download
References (1)
ab69875 has been referenced in 1 publication.
- Campa CC et al. Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes. Nat Chem Biol N/A:N/A (2018). PubMed: 29915378