Anti-MX1 antibody (ab95926)
Key features and details
- Rabbit polyclonal to MX1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-MX1 antibody
See all MX1 primary antibodies -
Description
Rabbit polyclonal to MX1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Dog -
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 and 246 of Human MX1.
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Positive control
- WB: H1299, HeLa, and Raji whole cell lysate; 293T, A431 and HepG2 whole cell lysate (ab7900) IHC-P: MDA-MB-468 xenograft
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Purified by antigen affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab95926 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (2) |
1/500 - 1/3000. Predicted molecular weight: 76 kDa.
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IHC-P | (6) |
1/100 - 1/500.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 76 kDa. |
IHC-P
1/100 - 1/500. |
Target
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Function
May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus. -
Sequence similarities
Belongs to the dynamin family.
Contains 1 GED domain. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 4599 Human
- Omim: 147150 Human
- SwissProt: P20591 Human
- Unigene: 517307 Human
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Alternative names
- Human interferon regulated resistance GTP binding protein MXA antibody
- IFI 78 antibody
- IFI 78K antibody
see all
Images
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Lane 1 : Anti-MX1 antibody (ab95926) at 1/1000 dilution
Lane 2 : Anti-MX1 antibody (ab95926)
Lane 1 : 293T whole cell lysate/extract
Lane 2 : Human MX-1 transfected 293T cells
Lysates/proteins at 30 µg per lane.
Secondary
All lanes : HRP-conjugated anti-rabbit IgG antibody
Predicted band size: 76 kDa -
Immunohistochemical analysis of paraffin embedded MDA-MB-468 xenograft, using ab95926 at a 1/500 dilution.
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All lanes : Anti-MX1 antibody (ab95926) at 1/5000 dilution
Lane 1 : H1299 cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : Raji cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 76 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (39)
ab95926 has been referenced in 39 publications.
- Jurczyszak D et al. ISG15 deficiency restricts HIV-1 infection. PLoS Pathog 18:e1010405 (2022). PubMed: 35333911
- Filipe IC et al. Comparison of tissue tropism and host response to enteric and respiratory enteroviruses. PLoS Pathog 18:e1010632 (2022). PubMed: 35789345
- Zhou M et al. Activation of cGAS-STING pathway - A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy. J Clin Lab Anal 36:e24631 (2022). PubMed: 36030554
- Pierini V et al. SERINC5 Can Enhance Proinflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles. J Virol 95:N/A (2021). PubMed: 33597208
- Lepelley A et al. Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A. J Exp Med 218:N/A (2021). PubMed: 34387651