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Product name
Anti-MYBPC1 antibody
See all MYBPC1 products (5) ...
Description
Mouse monoclonal to MYBPC1
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: DAYNVTLPAK VHVIDPPKII LDGLDADNTV TVIAGNKLRL EIPISGEPPP KAMWSRGDKA IMEGSGRIRT ESYPDSSTLV IDIAERDDSG VYHINLKN, corresponding to amino acids 506-604 of Human MYBPC1
DAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLV IDIAERDDSGVYHINLKN
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Regulation
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Motor Proteins >> Myosin
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Western blot - MYBPC1 antibody (ab55559)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55559 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Sequence similarities
Belongs to the immunoglobulin superfamily. MyBP family.
Contains 3 fibronectin type-III domains.
Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
Target information above from: UniProt accessionQ00872
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- skeletal muscle slow isoform antibody
- slow-type antibody
- C protein, skeletal muscle slow isoform antibody
see all
Database links
- Entrez Gene: 4604 Human
- Omim: 160794 Human
- SwissProt: Q00872 Human
- Unigene: 654589 Human
Anti-MYBPC1 antibody images:
Western blot - MYBPC1 antibody (ab55559)
Western blot against tagged recombinant protein immunogen using ab55559 MYBPC1 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa
References for Anti-MYBPC1 antibody (ab55559)
This product has been referenced in:
- Gurnett CA et al. Myosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1. Hum Mol Genet 19:1165-73 (2010). WB; Human.Read more (PubMed: 20045868) »
See 1 publication for this product
Publishing research using ab55559? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"