Anti-Macrophage Inflammatory Protein 1 beta antibody (Biotin) (ab84439)
- Product nameAnti-Macrophage Inflammatory Protein 1 beta antibody (Biotin)See all Macrophage Inflammatory Protein 1 beta primary antibodies ...
- DescriptionGoat polyclonal to Macrophage Inflammatory Protein 1 beta (Biotin)
- Tested applicationsWB, ELISA, Sandwich ELISA more details
- Species reactivityReacts with: Human
Highly pure (>98%) recombinant full length Human protein
- FormLyophilised:Centrifuge vial prior to opening. Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: PBS, pH 7.2
- Concentration information loading...
- Purification notesab84439 is purified by affinity chromatography and then biotinylated. Filter sterilised
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab84439 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
sELISA: Use at a concentration of 0.25 - 1 µg/ml. Detection limit for recombinant Human protein: 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
WB: Use at a concentration of 0.1 - 0.2 µg/ml. Detection limit for recombinant Human protein: 1.5 - 3.0 ng/lane, under reducing or non-reducing conditions. Predicted molecular weight: 10 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- FunctionMonokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
- Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
modificationsN-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.
- Cellular localizationSecreted.
- MIP 1 beta antibody Secreted protein G 26 antibodyACT 2 antibody
- ACT-2 antibodyACT2 antibodyAT744.1 antibodyAT744.2 antibodyC C motif chemokine 4 antibodyC C motif chemokine 4 like antibodyCC chemokine ligand 4 antibodyCC chemokine ligand 4L1d2 antibodyCC chemokine ligand 4L2 antibodyCCL4 antibodyCCL4_HUMAN antibodyccl4l 1 antibodyCCL4L antibodyCCL4L1 antibodyChemokine (C C motif) ligand 4 antibodyChemokine (C C motif) ligand 4 like 1 antibodyChemokine (C C motif) ligand 4 like 1, telomeric antibodyChemokine (C C motif) ligand 4 like 2 antibodyChemokine CC Motif Ligand 4 antibodyG 26 antibodyG 26 T lymphocyte secreted protein antibodyG-26 T-lymphocyte-secreted protein antibodyHC21 antibodylag 1 antibodyLAG-1 antibodyLAG1 antibodyLymphocyte activation gene 1 antibodyLymphocyte activation gene 1 protein antibodyMacrophage inflammatory protein 1 beta antibodyMacrophage inflammatory protein 1-beta antibodyMacrophage inflammatory protein 1b2 antibodyMGC104418 antibodyMGC126025 antibodyMGC126026 antibodyMIP-1-beta antibodyMIP-1-beta(1-69) antibodyMIP-1-beta(3-69) antibodyMIP1 beta antibodyMIP1B antibodyMIP1B1 antibodyMonocyte adherence induced protein 5 alpha antibodyPAT 744 antibodyProtein H400 antibodySCYA2 antibodySCYA4 antibodySCYA4L antibodySecreted protein G26 antibodySIS gamma antibodySIS-gamma antibodySmall inducible cytokine A4 (homologous to mouse Mip 1b) antibodySmall inducible cytokine A4 antibodySmall-inducible cytokine A4 antibodyT cell activation protein 2 antibodyT-cell activation protein 2 antibody
References for Anti-Macrophage Inflammatory Protein 1 beta antibody (Biotin) (ab84439)
ab84439 has not yet been referenced specifically in any publications.