Anti-Macrophage Inflammatory Protein 3 alpha antibody [MM0145-3K21] (ab89395)

Overview

• Product nameAnti-Macrophage Inflammatory Protein 3 alpha antibody [MM0145-3K21]See all Macrophage Inflammatory Protein 3 alpha primary antibodies ...
• Description
  Mouse monoclonal [MM0145-3K21] to Macrophage Inflammatory Protein 3 alpha
• Tested applicationsWB, Neutralising more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length Human protein.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS
• Concentration information loading...
• PurityProtein G purified
• Purification notesThe IgG fraction of culture supernatant was purified by Protein G affinity chromatography.
• Clonality Monoclonal
• Clone numberMM0145-3K21
• IsotypeIgG1
• Research Areas
  • Immunology
  • Innate Immunity
  • Chemokines
  • Beta Chemokines (CC)

  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

Applications

Target

• FunctionChemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
• Tissue specificityExpressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
• Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
• Post-translational
  modificationsC-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
• Cellular localizationSecreted.

Target information above from: UniProt accession P78556 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 6364 Human
  • Omim: 601960 Human
  • SwissProt: P78556 Human
  • Unigene: 75498 Human

• Alternative names
  Beta-chemokine exodus-1 antibodyC-C motif chemokine 20 antibodyCC chemokine LARC antibody

  CCL20 antibodyCCL20(2-70) antibodyCCL20_HUMAN antibodyChemokine (C C motif) ligand 20 antibodyChemokine CC motif ligand 20 antibodyCKb4 antibodyExodus 1 antibodyLARC antibodyLiver and activation-regulated chemokine antibodyMacrophage inflammatory protein 3 alpha antibodyMIP 3 alpha antibodyMIP 3A antibodyMIP-3-alpha antibodyMIP3A antibodySCYA20 antibodySmall inducible cytokine A20 antibodySmall inducible cytokine subfamily A (Cys Cys) member 20 antibodySmall-inducible cytokine A20 antibodyST38 antibody

  see all