Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab25123)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab25123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB 1/2000. Predicted molecular weight: 11 kDa.
IP 1/500.

Target

  • FunctionChemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
  • Tissue specificityExpressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
  • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications
    C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
  • Cellular localizationSecreted.
  • Target information above from: UniProt accession P78556 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • Beta-chemokine exodus-1 antibody
    • C-C motif chemokine 20 antibody
    • CC chemokine LARC antibody
    • Ccl20 antibody
    • CCL20(2-70) antibody
    • CCL20_HUMAN antibody
    • Chemokine (C C motif) ligand 20 antibody
    • Chemokine CC motif ligand 20 antibody
    • CKb4 antibody
    • Exodus 1 antibody
    • LARC antibody
    • Liver and activation-regulated chemokine antibody
    • Macrophage inflammatory protein 3 alpha antibody
    • MIP 3 alpha antibody
    • MIP 3A antibody
    • MIP-3-alpha antibody
    • MIP-3a antibody
    • MIP3A antibody
    • SCYA20 antibody
    • Small inducible cytokine A20 antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 20 antibody
    • Small-inducible cytokine A20 antibody
    • ST38 antibody
    see all

Anti-Macrophage Inflammatory Protein 3 alpha antibody images

  • Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab25123) at 1/2000 dilution + Transient transfected cells.

    Predicted band size : 11 kDa

References for Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab25123)

This product has been referenced in:
  • Qi W  et al. High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism. Nephrol Dial Transplant 22:3147-53 (2007). Read more (PubMed: 17664181) »

See 1 Publication for this product

Product Wall

According to our records, ab54429, ab25123, ab1420 and ab8098 was proving difficult to use and we were in contact in order to help resolve the issue. Looking at our correspondence, it appears that we are awaiting more details in order to help us be...

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Thank you for confirming the details. I would need the purchase order number to send you the requested antibodies. I am sorry without correct purchase order number of each antibody; I will not be able to send you these products. I hope th...

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Thank you for your enquiry regarding ab1420, ab8098, ab54429 and ab25123 and for taking the time to provide some useful details of the experiments. I am very sorry to hear that you are having problems with this antibody. Additionally, thank you for sup...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"