You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab9349)

Submit an Abreview Q&A (2)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab9349 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA
  • Application notesELISA:
    This antibody can be used at a concentration of 1-2 µg/ml, as a capture antibody in conjunction with a compatible secondary reagent to yield satisfactory results in a sandwich ELISA (using 100µl/well antibody solution).

    • Target

    • FunctionChemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
    • Tissue specificityExpressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
    • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications      C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
    • Cellular localizationSecreted.

      • Target information above from: UniProt accession P78556 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          Beta-chemokine exodus-1 antibodyC-C motif chemokine 20 antibodyCC chemokine LARC antibody
          CCL20 antibodyCCL20(2-70) antibodyCCL20_HUMAN antibodyChemokine (C C motif) ligand 20 antibodyChemokine CC motif ligand 20 antibodyCKb4 antibodyExodus 1 antibodyLARC antibodyLiver and activation-regulated chemokine antibodyMacrophage inflammatory protein 3 alpha antibodyMIP 3 alpha antibodyMIP 3A antibodyMIP-3-alpha antibodyMIP3A antibodySCYA20 antibodySmall inducible cytokine A20 antibodySmall inducible cytokine subfamily A (Cys Cys) member 20 antibodySmall-inducible cytokine A20 antibodyST38 antibody
        see all

      References for Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab9349)

      ab9349 has not yet been referenced specifically in any publications.

      Publishing research using ab9349 ? Please let us know so that we can cite the reference in this datasheet

      Product Wall

      Submit an Abreview for ab9349 Submit a Question for ab9349

      Displaying 1 - 2 of 2 results for Abreviews and Q&A

      10
      Votes: Highest First

      I investigate the NH2-terminally truncated forms of the chemokine MIP-3 alpha, therefore I am looking for antibodies able to recognize the COOH-terminal region of MIP-3 alpha. I would be very pleased whether you can indicate me against which epitope is t...

      Read More

      Thank you for your enquiry. Unfortunately, we do not have more information about this antibody. We will update the on-line datasheet of this product as soon as we get more data. We apologize for any inconvenience caused.

      Answers to the form are below 1. Please describe the problem (high background, no signal, non-specific colour development, poor standard curve etc). there is a low signal that is fairly uniform across the plate including the background and top conce...

      Read More

      Thank you for your enquiry and your detailed protocol. We have tested lot number 39877 and have found that its performance did not compare as well as other lot. We will therefore arrange a replacement vial of a new batch. This batch should be availab...

      Read More

      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"