Overview
Product nameMacrophage Inflammatory Protein 3 alpha proteinSee all Macrophage Inflammatory Protein 3 alpha proteins and peptides ...
Protein descriptionRecombinant fragment corresponding to amino acids 29-100 of Chicken Macrophage Inflammatory Protein 3 alpha produced in yeast; 72 amino acids, Predicted MWt 8.3kDa (Swiss-Prot Q8QG55).
Expression hostSaccharomyces cerevisiae
Properties
Purity> 95
% by SDS-PAGE
Purification notesab87396 is purified by Ion-exchange chromatography.
FormLyophilised:Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Storage instructionsStore at -20°C. Stable for 12 months at -20°C
Storage bufferPreservative: None
Constituents: 10% Trehalose, 1.0X PBS
Concentration information loading...
Sequence notesQSNQDCCLSY SKVRLPRKVI KGFTEQLSGE VCDIDAIIFH TVRGLKACVN PKEDWVKKHL LFLSQKLKRM SM
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab87396
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| SDS-PAGE |
SDS-PAGE: Use at an assay dependent dilution. |
Protein info
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Alternative names
Beta-chemokine exodus-1C-C motif chemokine 20CC chemokine LARC
CCL20CCL20(2-70)CCL20_HUMANChemokine (C C motif) ligand 20Chemokine CC motif ligand 20CKb4Exodus 1LARCLiver and activation-regulated chemokineMacrophage inflammatory protein 3 alphaMIP 3 alphaMIP 3AMIP-3-alphaMIP3ASCYA20Small inducible cytokine A20Small inducible cytokine subfamily A (Cys Cys) member 20Small-inducible cytokine A20ST38
see all
FunctionChemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
Tissue specificityExpressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
Post-translational
modificationsC-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Cellular localizationSecreted.
References for Macrophage Inflammatory Protein 3 alpha protein (ab87396)
ab87396
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
