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Products:Immunology >> Innate Immunity >> Macrophage / Inflamm.
Overview
Product name
Anti-Macrophage Inflammatory Protein 3 beta antibody - C-terminal
See all Macrophage Inflammatory Protein 3 beta products (5) ...
Description
Rabbit polyclonal to Macrophage Inflammatory Protein 3 beta - C-terminal
Tested applications
ELISA, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide from the C terminal region of Human Macrophage Inflammatory Protein 3 beta, conjugated to KLH
Positive control
Human hepatocarcinoma or colon carcinoma tissue
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Immunology >> Innate Immunity >> Chemokines >> Beta Chemokines (CC)
Immunology >> Innate Immunity >> Macrophage / Inflamm.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Macrophage Inflammatory Protein 3 beta antibody (ab80145)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab80145 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/1000ELISA: 1/1000
IHC-P: 1/50 - 1/100.
Target
Relevance
MIP3 chemokines are among many novel beta chemokines recently identified through bioinformatics in the Expressed Sequence Tag (EST) database. They are distantly related to other beta chemokines (20-30% aa sequence homology). MIP3 chemokines are useful probes for studying the biology of inflammation and cell migration. Their expression is strongly up-regulated by inflammatory signals and down-regulated by the anti-inflammatory cytokine IL10. MIP3 beta is also known as ELC (EBI1-1 ligand chemokine) and is constitutively expressed in various lymphoid tissues (thymus, lymph nodes, appendix and spleen). MIP3 beta is a chemoattractant for cultured human lymphocytes, dendritic cells, human T lymphoblastoid CEM NKR2 and hemopoietic progenitor cells. It may be involved in G Protein activation in human NK cells. MIP3 beta is a unique functional ligand for CCR7. The MIP3 beta gene has been mapped to chormosome 9p13.
Cellular localization
Secreted
Alternative names
- Beta chemokine exodus 3 antibody
- C C chemokine ligand 19 antibody
- CC chemokine ligand 19 antibody
see all
Database links
- Entrez Gene: 6363 Human
- Omim: 602227 Human
- SwissProt: Q5VZ75 Human
- SwissProt: Q6IBD6 Human
- SwissProt: Q99731 Human
- Unigene: 50002 Human
Anti-Macrophage Inflammatory Protein 3 beta antibody - C-terminal images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Macrophage Inflammatory Protein 3 beta antibody (ab80145)
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human hepatocarcinoma (left) and colon carcinoma (right) tissue sections, using 1/50-1/100 ab80145, in conjunction with a peroxidase-conjugated secondary antibody, followed by AEC (left) or DAB (right) staining.
References for Anti-Macrophage Inflammatory Protein 3 beta antibody - C-terminal (ab80145)
ab80145 has not yet been referenced specifically in any publications.
Publishing research using ab80145? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"