|
|
|
|
Western blot - Mad2L1 antibody (ab55452)

(enlarge)
|
|
|
|
|
Product Name
|
Mad2L1 antibody
|
| |
See all Mad2L1 antibodies (6)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Mouse monoclonal to Mad2L1
|
|
Immunogen
|
Recombinant full length protein, corresponding to amino acids 1-206 of Human Mad2L1
|
|
Reacts with
(species key)
|
Hu
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Nuclear
|
|
Research areas
|
Cancer >> Cell cycle >> Cell division Cell Biology >> Cell Cycle >> Cell Division >> Other cell division antibodies Tags & Cell Markers >> Subcellular Markers >> Nucleus >> Other Nuclear Bodies Cell Biology >> Cell Cycle >> Cell Division >> Spindle
|
|
Relevance
|
Mad2L1 is required for the execution of the mitotic checkpoint which monitors the process of kinetochore spindle attachment and delays the onset of anaphase when this process is not complete. It inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
|
|
|
Mad2L1 antibody (ab55452)
|
|
Database links
|
The links below go to external sites and will open in a new browser window
|
|
Raised in
|
Mouse
|
|
Clonality
|
Monoclonal
|
|
Isotype
|
IgG2b
|
|
Light chain type
|
kappa
|
|
Purity
|
Protein G purified
|
|
Storage buffer
|
Preservative: None PBS, pH 7.2
|
|
Form
|
Liquid
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Mad2L1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
Mad2L1 antibody images:
|
Western blot - Mad2L1 antibody (ab55452)
Predicted band size : 24 kDa
Mad2L1 antibody (ab55452) at 1ug/lane + HeLa cell lysate at 25ug/lane.
|
| |
| |
|
Search PubMed (MEDLINE) for references to Mad2L1
|
| |
Mad2L1 antibody - more information
|
Customer reviews (feedback) regarding Mad2L1 antibody |
Customer FAQs regarding Mad2L1 antibody |
Protocols for Mad2L1 antibody |
Price and availability of products related to Mad2L1 antibody |
| |
Mad2L1 antibody - other tools:
|
Contact Abcam with a Technical Enquiry about Mad2L1 antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"