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Anti-Mast Cell Tryptase antibody [AA1], prediluted (ab74506)

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Overview

  • Product nameAnti-Mast Cell Tryptase antibody [AA1], predilutedSee all Mast Cell Tryptase primary antibodies ...
  • Description
    Mouse monoclonal [AA1] to Mast Cell Tryptase, prediluted
  • Tested applicationsIHC-P more details
  • Species reactivity
    Reacts with: Cat, Dog, Human, Monkey
  • Immunogen

    Full length Human Mast Cell Tryptase purified from lung tissue.

  • Positive controlHuman tonsil tissue.
  • General notes


    ab75406 is an excellent marker for Mast cells, and does not bind to any other cell type in IHC.

Properties

Applications

Our Abpromise guarantee covers the use of ab74506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P
  • Application notesIHC-P: Ready-to-Use. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • RelevanceMast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase. Human Mast Cell Tryptase is considered to be an important marker of mast cell activation as well as an important mediator of inflammation.
    • Cellular localizationSecreted. Note: released from the secretory granules upon mast cell activation.
    • Database links
      • Alternative names
          alpha II antibodyEC 3.4.21.59 antibodyLung tryptase antibody
          Mast cell alpha II tryptase antibodyMast cell beta I tryptase antibodyMast cell protease 7 antibodyMast cell protease II antibodyMCP 7 antibodyMMCP 7 antibodyPituitary tryptase antibodySkin tryptase antibodyTPS 1 antibodyTPS1 antibodyTPS2 antibodyTPSAB1 antibodyTPSAB1 protein antibodyTPSB1 antibodyTryptase 1 antibodyTryptase alpha 1 antibodytryptase alpha I included antibodyTryptase alpha II antibodytryptase alpha II included antibodytryptase alpha included antibodytryptase alpha/beta 1 antibodyTryptase beta 1 antibodytryptase beta I included antibodyTryptase I antibodytryptase I included antibodyTryptase III antibodyTryptase skin antibody
        see all

      Anti-Mast Cell Tryptase antibody [AA1], prediluted images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Mast Cell Tryptase antibody [AA1], prediluted (ab74506)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Mast Cell Tryptase antibody [AA1], prediluted (ab74506)
        Formalin-fixed, paraffin-embedded human tonsil stained with ab74506 using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of mast cells.

      References for Anti-Mast Cell Tryptase antibody [AA1], prediluted (ab74506)

      This product has been referenced in:
      • Walls AF  et al. Production and characterization of monoclonal antibodies specific for human mast cell tryptase. Clin Exp Allergy 20:581-9 (1990). Read more (PubMed: 2253091) »
      • Walls AF  et al. Immunohistochemical identification of mast cells in formaldehyde-fixed tissue using monoclonal antibodies specific for tryptase. J Pathol 162:119-26 (1990). Read more (PubMed: 2250189) »

      See all 3 Publications for this product

      Publishing research using ab74506 ? Please let us know so that we can cite the reference in this datasheet

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"