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Anti-Matrin 3 antibody [2539C3a] (ab53748)

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Overview

Product name

Anti-Matrin 3 antibody [2539C3a]
See all Matrin 3 products (5) ...

Description

Mouse monoclonal [2539C3a] to Matrin 3

Tested applications

WB, Dot Blotmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant human MATR3 protein.

Properties

Form

Liquid

Storage instructions

Store at 4°C for up to one year. Upon use, aliquot and store at -20°C or -80°C.

Storage buffer

Preservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

2539C3a

Isotype

IgG1

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Epigenetics and Nuclear Signaling >> Chromosome Structure >> Scaffold Proteins

  • Western blot - Matrin 3 antibody [2539C3a] (ab53748)Western blot - Matrin 3 antibody [2539C3a] (ab53748) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab53748 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.

Involvement in disease

Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.

Sequence similarities

Contains 1 matrin-type zinc finger.
Contains 2 RRM (RNA recognition motif) domains.

Cellular localization

Nucleus matrix.

Target information above from: UniProt accessionP43243 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • MATR3 antibody
  • MATR3_HUMAN antibody
  • Matrin-3 antibody
  • Matrin3 antibody

Database links

Anti-Matrin 3 antibody [2539C3a] images:

  Western blot - Matrin 3 antibody [2539C3a] (ab53748)

Western blot - Matrin 3 antibody [2539C3a] (ab53748)

Anti-Matrin 3 antibody [2539C3a] (ab53748) + recombinant immunising protein

Predicted band size : 95 kDa

References for Anti-Matrin 3 antibody [2539C3a] (ab53748)

This product has been referenced in:

  • Antrobus Ret al. Proteomic analysis of cells in the early stages of herpes simplex virus type-1 infection reveals widespread changes in the host cell proteome. Proteomics 9:3913-27 (2009).Read more (PubMed: 19670248) »

See 1 publication for this product

Publishing research using ab53748? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"