Overview
- Product nameAnti-Melatonin Receptor 1B antibodySee all Melatonin Receptor 1B primary antibodies ...
- DescriptionGoat polyclonal to Melatonin Receptor 1B
- Tested applicationsIHC-P more details
- Species reactivityReacts with: Human
Predicted to work with: Cynomolgus Monkey, Rhesus monkey - Immunogen
Synthetic peptide: QDASKGSHAEGLQSP, by a Cysteine residue linker, corresponding to C terminal amino acids 334-347 of Human Melatonin Receptor 1B (NP_005950.1.).
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 -
Concentration information loading... - PurityImmunogen affinity purified
- Purification notesPurified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab92339 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| IHC-P | IHC-P: Use a concentration of 3 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
- FunctionHigh affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
- Tissue specificityExpressed in retina and less in brain and hippocampus.
- Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
- Cellular localizationCell membrane.
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Database links
- Entrez Gene: 4544 Human
- Entrez Gene: 695629 Rhesus monkey
- Omim: 600804 Human
- SwissProt: P49286 Human
- Unigene: 569039 Human
Target information above from: UniProt accession
P49286
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- FGQTL2 antibodyMel 1b antibodyMel 1b melatonin receptor antibody
- Mel 1B R antibodyMEL-1B-R antibodyMel1b antibodyMel1b melatonin receptor antibodyMel1b receptor antibodyMel1BR antibodymelatonin receptor 1B antibodyMelatonin receptor MEL 1B antibodyMelatonin receptor MEL1B antibodyMelatonin receptor type 1B antibodyMT 2 antibodyMT 2 melatonin receptor antibodyMT2 antibodyMT2 melatonin receptor antibodyMtnr 1b antibodyMtnr1b antibodyMTR1B_HUMAN antibody
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Anti-Melatonin Receptor 1B antibody images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Melatonin Receptor 1B antibody (ab92339)ab92339 (3.8µg/ml) staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
References for Anti-Melatonin Receptor 1B antibody (ab92339)
ab92339 has not yet been referenced specifically in any publications.
