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Product Name
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Membrin antibody
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See all Membrin antibodies (4)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Membrin
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Immunogen
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Synthetic peptide: RNFQHRRQAKEQQERQRDE conjugated to KLH, corresponding to amino acids 85-103 of Rat Membrin.
BLAST 'RNFQHRRQAKEQQERQRDE' with  or 
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Reacts with
(species key)
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Hu, Ms, Rat, Chk, Cow, Dog, Dm, Hm, Mk, Pig, Rb, Shp
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 2 µg/ml. This concentration detects Membrin in 20 µg of Rat Brain Tissue Extract using ECL detection. Predicted molecular weight: 24.8 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Rat Brain Tissue Extract
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Cellular localization
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Golgi Apparatus
Type IV membrane protein
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Research areas
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Signal Transduction >> Protein Trafficking >> Vesicle Transport >> SNAPs & SNAREs
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Relevance
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Membrin is a 27 kDa integral membrane protein on the surface of the Golgi apparatus that serves as a tSNARE in ER to Golgi transport. GS27 is a member of a protein complex that consists of cis-Golgi vesicle receptor syntaxin 5 and GS28, vSNARE rbet1 and rsec22, and rsly1. Immunoprecipitation analysis has shown that there are two subcomplexes within this complex: one contains syntaxin 5 and GOS28 and the other one contains syntaxin 5, GS27/membrin, rsec22 and rbet1. These complexes are postulated to direct the fusion of ER-derived vesicles with Vesicular tubular cluster (VTC), and the fusion of VTCs to form cis-Golgi compartment.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: None
Constituents: Borate Buffered Saline. pH 8.4
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Membrin antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Membrin
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Membrin antibody - more information
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