Anti-Mesothelin antibody [SPM143], prediluted (ab15231)
- Product nameAnti-Mesothelin antibody [SPM143], predilutedSee all Mesothelin primary antibodies ...
- DescriptionMouse monoclonal [SPM143] to Mesothelin, prediluted
- Tested applicationsIHC-P more details
- Species reactivityReacts with: Human
Recombinant protein corresponding to the membrane-bound form of the human mesothelin molecule.
- Positive control
- Storage instructionsStore at +4°C.
- Storage bufferPreservative: 0.1% Sodium Azide
Constituents: BSA, 10mM PBS, pH 7.4
- PurityTissue culture supernatant
- Clonality Monoclonal
- Clone numberSPM143
- Research Areas
Our Abpromise guarantee covers the use of ab15231 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- FunctionMembrane-anchored forms may play a role in cellular adhesion.
Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
- Tissue specificityExpressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
- Involvement in diseaseNote=Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.
- Sequence similaritiesBelongs to the mesothelin family.
modificationsBoth MPF and the cleaved form of mesothelin are N-glycosylated.
Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.
- Cellular localizationSecreted and Cell membrane. Golgi apparatus.
- CAK 1 antibody
- CAK1 antibody
- CAK1 antigen antibody
- cleaved form antibody
- Megakaryocyte potentiating factor antibody
- Mesothelin antibody
- Mesothelin isoform 1 precursor antibody
- MPF antibody
- MSLN antibody
- MSLN_HUMAN antibody
- Pre pro megakaryocyte potentiating factor antibody
- Pre-pro-megakaryocyte-potentiating factor antibody
- SMR antibody
- SMRP antibody
- Soluble MPF mesothelin related protein antibody
References for Anti-Mesothelin antibody [SPM143], prediluted (ab15231)
ab15231 has not yet been referenced specifically in any publications.