Anti-Mesothelin antibody (ab96869)
- Product nameAnti-Mesothelin antibodySee all Mesothelin primary antibodies ...
- DescriptionRabbit polyclonal to Mesothelin
- Tested applicationsWB, IHC-P more details
- Species reactivityReacts with: Human
Recombinant protein fragment corresponding to a region within amino acids 44 and 438 of Human Mesothelin (NP_037536).
- Positive control
- WB: 293T cell lysate IHC-P: serous OVCA
- Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
- Concentration information loading...
- PurityImmunogen affinity purified
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab96869 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: 1/500 - 1/3000. Predicted molecular weight: 69 kDa.|
- FunctionMembrane-anchored forms may play a role in cellular adhesion.
Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
- Tissue specificityExpressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
- Involvement in diseaseNote=Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.
- Sequence similaritiesBelongs to the mesothelin family.
modificationsBoth MPF and the cleaved form of mesothelin are N-glycosylated.
Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.
- Cellular localizationSecreted and Cell membrane. Golgi apparatus.
- CAK 1 antibody
- CAK1 antibody
- CAK1 antigen antibody
- cleaved form antibody
- Megakaryocyte potentiating factor antibody
- Mesothelin antibody
- Mesothelin isoform 1 precursor antibody
- MPF antibody
- Msln antibody
- MSLN_HUMAN antibody
- Pre pro megakaryocyte potentiating factor antibody
- Pre-pro-megakaryocyte-potentiating factor antibody
- SMR antibody
- SMRP antibody
- Soluble MPF mesothelin related protein antibody
Anti-Mesothelin antibody images
Anti-Mesothelin antibody (ab96869) at 1/1000 dilution + 293T whole cell lysate at 30 µg
Predicted band size : 69 kDa
Immunohistochemical analysis of Mesothelin in paraffin embedded serous OVCA, using ab96869 at a 1/100 dilution.
References for Anti-Mesothelin antibody (ab96869)
ab96869 has not yet been referenced specifically in any publications.