Anti-Metabotropic Glutamate Receptor 7/MGLUR7 antibody (ab85343)
Key features and details
- Goat polyclonal to Metabotropic Glutamate Receptor 7/MGLUR7
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Metabotropic Glutamate Receptor 7/MGLUR7 antibody
See all Metabotropic Glutamate Receptor 7/MGLUR7 primary antibodies -
Description
Goat polyclonal to Metabotropic Glutamate Receptor 7/MGLUR7 -
Host species
Goat -
Specificity
ab85343 is expected to recognize both reported isoforms (NP_000835.1; NP_870989.1). -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Human Brain (Cerebellum), Mouse and Rat Brain lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab85343 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab85343 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).
1 hour primary incubation is recommended for this product. |
Notes |
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WB
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa). 1 hour primary incubation is recommended for this product. |
Target
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Function
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. -
Tissue specificity
Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4. -
Sequence similarities
Belongs to the G-protein coupled receptor 3 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2917 Human
- Omim: 604101 Human
- SwissProt: Q14831 Human
- Unigene: 606393 Human
- Unigene: 660131 Human
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Alternative names
- FLJ40498 antibody
- GLUR7 antibody
- Glutamate receptor metabotropic 7 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab85343 has not yet been referenced specifically in any publications.