Anti-Methylated Lysine antibody (FITC) (ab53527)

Overview

• Product nameAnti-Methylated Lysine antibody (FITC)See all Methylated Lysine primary antibodies ...
• Description
  Rabbit polyclonal to Methylated Lysine (FITC)
• ConjugationFITC
• Conjugation notesFITC/Ab molar ratio: approximately 10:1
• SpecificityThis antibody recognizes proteins methylated on lysine residues (mono and di-methylysine). It does not cross-react with acetylated proteins. Cross-reactivity to trimethyllysine has not been tested.
• Tested applicationsICC/IF more details
• Species reactivity
  Reacts with: Mouse, Human
  Predicted to work with: a wide range of other species
• Immunogen

  Methylated protein [s] conjugated to KLH.

• Positive controlHuman melanoma cells (MMRU).

Properties

• FormLiquid
• Storage instructionsStore at -20°C. Stable for 12 months at -20°C
• Storage bufferPreservative: None
  Constituents: 50% Glycerol, PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesThis antibody was affinity purified using N epsilon-monomethyllysine and dimethyllysine on Agarose as an affinity matrix.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Amino acid metabolism

  • Signal Transduction
  • Metabolism
  • Amino Acids

  • Epigenetics and Nuclear Signaling
  • Histones
  • H3
  • Methylated

  • Epigenetics and Nuclear Signaling
  • Histones
  • H2A
  • Methylated

  • Epigenetics and Nuclear Signaling
  • Histones
  • H2B
  • Methylated

  • Epigenetics and Nuclear Signaling
  • Histones
  • H4
  • Methylated

  • Cell Biology
  • Other Antibodies
  • Other Antibodies

Applications

Target

• RelevanceMany proteins are post translationally modified. Modifications such as phosphorylation, glycosylation, ubiquitination and methylation have been shown to play an important role in the development, physiology and disease of animals and plants. Histone lysine methylation is regarded as a very stable modification with important functions in epigenetic gene control and for organizing chromatin domains.

• Alternative names
  Dimethylysine antibodyMethyl lysine antibodyN epsilon dimethyl lysine antibody

  N epsilon mono methyllysine antibodyN epsilon trimethyl lysine antibodyN(epsilon) trimethyl lysine antibodyTrimethyl lysine antibody

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Anti-Methylated Lysine antibody (FITC) images

• 

  Immunocytochemistry/ Immunofluorescence - MEK1 antibody (FITC) (ab53527)
  This image shows human melanoma (MMRU) cells stained with ab53527 at 1/50 dilution.