Metoprolol tartrate, beta1 Adrenoceptor antagonist (ab120711)
Key features and details
- β1 Adrenoceptor antagonist
- CAS Number: 56392-17-7
- Purity: > 99%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Metoprolol tartrate, beta1 Adrenoceptor antagonist -
Description
β1 Adrenoceptor antagonist -
Biological description
β1 Adrenoceptor antagonist (Ki values are 47, 2960 and 10100 nM for β1, β2 and β3, respectively). Systemically active following oral administration.
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Purity
> 99% -
CAS Number
56392-17-7 -
Chemical structure
Properties
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Chemical name
1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemitartrate -
Molecular weight
342.41 -
Molecular formula
C15H25NO3.0.5C4H6O6 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (2)
ab120711 has been referenced in 2 publications.
- Giurdanella G et al. The Anti-Inflammatory Effect of the ß1-Adrenergic Receptor Antagonist Metoprolol on High Glucose Treated Human Microvascular Retinal Endothelial Cells. Cells 11:N/A (2021). PubMed: 35011613
- Lai J et al. ß-Adrenoceptor signaling regulates proliferation and contraction of human bladder smooth muscle cells under pathological hydrostatic pressure. J Cell Biochem 120:17872-17886 (2019). PubMed: 31161623