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Product Name
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Mib1/Mindbomb antibody
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See all Mib1/Mindbomb antibodies (5)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Mib1/Mindbomb
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Note on antibody grade |
Fast-Track antibodies
- Immunogen affinity purified
- high ELISA titre values
- released early (to accelerate your research)
- 950 Abpoints to the 1st researcher
who submits conclusive data (positive or negative):
Read the Fast-Track antibody Terms of Use
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Immunogen
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Synthetic peptide conjugated to KLH derived from within residues 900 - 1000 of Mouse Mib1/Mindbomb. (Peptide available as ab43645.)
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Predicted to react
(species key)
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Hu, Ms
(Due to sequence homology)
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Abreviews
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Application notes
(see key)
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Recommended dilutions
This antibody gave a positive result in ELISA against the immunizing peptide (ab43645).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cell Membrane and Cytoplasmic
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Research areas
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Stem Cells >> Signaling Pathways >> Notch >> Cytoplasmic
Stem Cells >> Signaling Pathways >> Notch >> Surface Molecules
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Relevance
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E3 ubiquitin ligase protein mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. It positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
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Mib1/Mindbomb antibody (ab43302) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Batch dependent within range: 0.50 - 1.00 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Mib1/Mindbomb antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for Mib1/Mindbomb antibody images, references, products related to ab43302 and other tools.
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Mib1/Mindbomb antibody images:
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This Fast-Track antibody is not yet fully characterised. These images represent inconclusive preliminary data.
Please read the definition of 'Fast-Track antibody'
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 Immunohistochemistry (PFA perfusion fixed frozen sections) - Mib1/Mindbomb antibody (ab43302)
ab43302 staining mouse brain tissue by IHC-FoFr. This antibody stained varicose fibers in the mouse habenula and hippocampus. The picture shows the staining obtained at the level of the habenula. The tissues were fixed with 4% PFA and later postfixed overnight in the same fixative. They were cryoprotected in 30% sucrose and cut using a cryostat. The primary antibody was diluted 1/1000 and incubated with the sample for 18 hrs at 20°C. An Alexa Fluor® 488 conjugated goat anti-rabbit was used as the secondary. Please refer to abreview for further details. This image is courtesy of an Abreview submitted by Dr Sophie Pezet
See Abreview
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Search PubMed (MEDLINE) for references to Mib1/Mindbomb
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Mib1/Mindbomb antibody - more information
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Customer reviews (feedback) regarding Mib1/Mindbomb antibody |
Customer FAQs regarding Mib1/Mindbomb antibody |
Protocols for Mib1/Mindbomb antibody |
Price and availability of products related to Mib1/Mindbomb antibody |
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Mib1/Mindbomb antibody - related products:
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Mib1/Mindbomb antibody - other tools:
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Contact Abcam with a Technical Enquiry about Mib1/Mindbomb antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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