Anti-Mitofusin 1 antibody (ab111271)

Overview

• Product nameAnti-Mitofusin 1 antibodySee all Mitofusin 1 primary antibodies ...
• Description
  Goat polyclonal to Mitofusin 1
• Tested applicationsIHC-P more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide from Human Mitofusin 1.

• Positive controlHuman Adrenal and Human Uterus tissues.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferpH: 7.30
  Preservative: 0.02% Sodium azide
  Constituents: Tris buffered saline, 0.5% BSA
• Concentration information loading...
• PurityProtein G purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitophagy fission and fusion

  • Signal Transduction
  • Second Messenger
  • Nucleotide Messenger
  • GTP

  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Mitochondria

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Parkinson's disease
  • Other

Applications

Target

• FunctionEssential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
• Tissue specificityUbiquitous. Expressed at slightly higher level in kidney and heart. Isoform 2 may be overexpressed in some tumors, such as lung cancers.
• Sequence similaritiesBelongs to the mitofusin family.
• Post-translational
  modificationsUbiquitinated by MARCH5.
• Cellular localizationCytoplasm and Mitochondrion outer membrane.

Target information above from: UniProt accession Q8IWA4 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 55669 Human
  • Entrez Gene: 55669 Human
  • Omim: 608506 Human
  • SwissProt: Q8IWA4 Human
  • SwissProt: Q8IWA4 Human
  • Unigene: 478383 Human

• Alternative names
  Fzo homolog antibodyHfzo1 antibodyHfzo2 antibody

  MFN 1 antibodyMfn1 antibodyMFN1_HUMAN antibodyMitochondrial transmembrane GTPase Fzo 1 antibodyMitochondrial transmembrane GTPase FZO 2 antibodyMitochondrial transmembrane GTPase FZO1B antibodyMitofusin 1 antibodyMitofusin-1 antibodyMitofusin1 antibodyPutative transmembrane GTPase antibodyTransmembrane GTPase MFN1 antibody

  see all

Anti-Mitofusin 1 antibody images

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Mitofusin 1 antibody (ab111271)
  ab111271, at 3.75µg/ml, staining Mitofusin 1 in formalin-fixed, paraffin-embedded Human Adrenal tissue by Immunohistochemistry.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Mitofusin 1 antibody (ab111271)
  ab111271, at 3.75µg/ml, staining Mitofusin 1 in formalin-fixed, paraffin-embedded Human Uterus tissue by Immunohistochemistry.