Anti-Monoamine Oxidase B/MAOB antibody (ab137778)
Key features and details
- Rabbit polyclonal to Monoamine Oxidase B/MAOB
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Monoamine Oxidase B/MAOB antibody
See all Monoamine Oxidase B/MAOB primary antibodies -
Description
Rabbit polyclonal to Monoamine Oxidase B/MAOB -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat, Cow, Dog, Pig -
Immunogen
Recombinant fragment corresponding to Human Monoamine Oxidase B/MAOB aa 163-501.
Database link: P27338 -
Positive control
- HepG2 and Mouse liver whole cell lysates; Human OVCA xenograft tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137778 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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WB |
1/500 - 1/3000. Predicted molecular weight: 59 kDa.
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Notes |
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IHC-P
1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
WB
1/500 - 1/3000. Predicted molecular weight: 59 kDa. |
Target
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Function
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. -
Sequence similarities
Belongs to the flavin monoamine oxidase family. -
Cellular localization
Mitochondrion outer membrane. - Information by UniProt
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Database links
- Entrez Gene: 338445 Cow
- Entrez Gene: 4129 Human
- Entrez Gene: 109731 Mouse
- Entrez Gene: 414909 Pig
- Entrez Gene: 25750 Rat
- Omim: 309860 Human
- SwissProt: P56560 Cow
- SwissProt: P27338 Human
see all -
Alternative names
- Adrenalin oxidase antibody
- Amine oxidase (flavin containing) antibody
- Amine oxidase [flavin-containing] B antibody
see all
Images
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Anti-Monoamine Oxidase B/MAOB antibody (ab137778) at 1/1500 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 59 kDa
7.5% SDS PAGE -
Anti-Monoamine Oxidase B/MAOB antibody (ab137778) at 1/1000 dilution + Mouse liver whole cell lysate at 50 µg
Predicted band size: 59 kDa
7.5% SDS PAGE -
Immunohistochemical analysis of paraffin embedded Human OVCA xenograft tissue labelling Monoamine Oxidase B/MAOB with ab137778 at 1/100 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab137778 has been referenced in 3 publications.
- Hayes HM et al. Preserved Left Ventricular Function despite Myocardial Fibrosis and Myopathy in the Dystrophin-Deficient D2.B10-Dmd mdx /J Mouse. Oxid Med Cell Longev 2022:5362115 (2022). PubMed: 35340200
- Choi JY et al. (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) Phenol Ameliorates MPTP-Induced Dopaminergic Neurodegeneration by Inhibiting the STAT3 Pathway. Int J Mol Sci 20:N/A (2019). PubMed: 31146332
- Lu DH et al. Impairment of social behaviors inArhgef10knockout mice. Mol Autism 9:11 (2018). PubMed: 29456827