Overview

  • Product nameAnti-Munc18c antibodySee all Munc18c primary antibodies ...
  • Description
    Rabbit polyclonal to Munc18c
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region between internal sequence amino acids 144-171 of Human Munc18c (NP_009200.2)

  • Positive control
    • SK-BR-3 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab112934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB 1/100 - 1/500. Predicted molecular weight: 68 kDa.

Target

  • FunctionTogether with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
  • Tissue specificityMegakaryocytes and platelets.
  • Sequence similaritiesBelongs to the STXBP/unc-18/SEC1 family.
  • Post-translational
    modifications
    Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.
  • Cellular localizationCytoplasm > cytosol. Cell membrane. In platelets, predominantly cytosolic. Low amounts membrane-associated.
  • Target information above from: UniProt accession O00186 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • Munc18 3 antibody
    • Munc18 3 antibody
    • Munc18 c antibody
    • Platelet Sec1 protein antibody
    • Protein unc-18 homolog 3 antibody
    • Protein unc-18 homolog C antibody
    • PSP antibody
    • STXB3_HUMAN antibody
    • STXBP 3 antibody
    • STXBP3 antibody
    • Sxtbp3 antibody
    • syntaxin 4 binding protein antibody
    • Syntaxin binding protein 3 antibody
    • Syntaxin-binding protein 3 antibody
    • Unc 18 3 antibody
    • Unc 18 homolog 3 antibody
    • Unc 18c antibody
    • Unc-18C antibody
    • Unc18-3 antibody
    see all

Anti-Munc18c antibody images

  • Anti-Munc18c antibody (ab112934) at 1/100 dilution + SK-BR-3 cell line lysates at 35 µg

    Predicted band size : 68 kDa

References for Anti-Munc18c antibody (ab112934)

ab112934 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam. We do not have data on whether ab112934 does recognize other members of the Munc18 family, but the region that was used as the peptide sequence has a very low level of homology with the other family members and I think i...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"