|
|
|
|
|
Product Name
|
Muscarinic Acetylcholine Receptor M4 antibody [18C7.2]
|
| |
See all Muscarinic Acetylcholine Receptor M4 antibodies (3)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Mouse monoclonal [18C7.2] to Muscarinic Acetylcholine Receptor M4
|
|
Immunogen
|
Muscarinic Acetylcholine Receptor M4 i3 loop (human), fused to a tag.
|
|
Reacts with
|
Rat, Mk
|
|
Predicted to react
(species key)
|
Hu
(Due to sequence homology)
|
|
Specificity
|
ab77956 reacts with Muscarinic acetylcholine receptor M4. There is no reactivity with the other subtypes.
|
|
Tested applications
(see key)
|
IHC-Fr, IP, WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 53 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
Transfected CHO cell lines
|
|
Cellular localization
|
Cell Membrane
|
|
Research areas
|
Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> Acetylcholine
Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> Muscarinic Receptors
|
|
Relevance
|
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and postassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Mouse
|
|
Clonality
|
Monoclonal
|
|
Clone number
|
18C7.2
|
|
Isotype
|
IgG1
|
|
Purity
|
Protein A purified
|
|
Storage buffer
|
Preservative: 0.1% Sodium Azide
Constituents: 0.25M Sodium chloride, 0.02M Phosphate buffer Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
|
|
Form
|
Liquid
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Store at +4°C.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to Muscarinic Acetylcholine Receptor M4
|
| |
Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] - more information
|
Customer reviews (feedback) regarding Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] |
Customer FAQs regarding Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] |
Protocols for Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] |
Price and availability of products related to Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] |
| |
Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] - related products:
|
|
|
| |
Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] - other tools:
|
Contact Abcam with a Technical Enquiry about Muscarinic Acetylcholine Receptor M4 antibody [18C7.2] |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
