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- Secondary antibodies
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Product name
Anti-Myeloperoxidase antibody [2A11] (HRP)
See all Myeloperoxidase products (30) ...
Description
Mouse monoclonal [2A11] to Myeloperoxidase (HRP)
Conjugation
HRP
Tested applications
Sandwich ELISA, ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
Full length native protein (purified) (Human)
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.05% Proclin
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein A purified
Purification notes
Purity tested by electrophoresis.
Clonality
Monoclonal
Clone number
2A11
Myeloma
Sp2/0
Isotype
IgG2a
Research areas
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Redox metabolism >> Antioxidants
Cancer >> Cancer Metabolism >> Cellular metabolic process
Cardiovascular >> Vasculature >> Vasculature Markers >> Pulmonary
Cardiovascular >> Vasculature >> Vasculature Markers >> Arterial
Cardiovascular >> Blood >> Other
Immunology >> Innate Immunity >> Macrophage / Inflamm.
Applications
Show applications key
Our Abpromise guarantee covers the use of ab24467 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Sandwich ELISA
ELISA
Application notes
ELISA: Use at an assay dependent dilution.
sELISA: Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [4A4] to Myeloperoxidase (ab10165).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Involvement in disease
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
Sequence similarities
Belongs to the peroxidase family. XPO subfamily.
Cellular localization
Lysosome.
Target information above from: UniProt accessionP05164
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
Database links
- Entrez Gene: 4353 Human
- Omim: 606989 Human
- SwissProt: P05164 Human
- Unigene: 458272 Human
References for Anti-Myeloperoxidase antibody [2A11] (HRP) (ab24467)
ab24467 has not yet been referenced specifically in any publications.
Publishing research using ab24467? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"