Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Related products
- Secondary antibodies
Reassurance, Refunds & Replacements
If your product does not perform as described on this datasheet, we will refund or replace your product...
Read our guarantee »Overview
Product name
Anti-Myeloperoxidase antibody [2A11]
See all Myeloperoxidase products (30) ...
Description
Mouse monoclonal [2A11] to Myeloperoxidase
Tested applications
ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
Full length native protein (purified) (Human).
General notes
Concentration varies from lot to lot and can be provided on request.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein A purified
Purification notes
Purity tested by electrophoresis.
Clonality
Monoclonal
Clone number
2A11
Myeloma
Sp2/0
Isotype
IgG2a
Research areas
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Redox metabolism >> Antioxidants
Cancer >> Cancer Metabolism >> Cellular metabolic process
Cardiovascular >> Vasculature >> Vasculature Markers >> Pulmonary
Cardiovascular >> Vasculature >> Vasculature Markers >> Arterial
Cardiovascular >> Blood >> Other
Immunology >> Innate Immunity >> Macrophage / Inflamm.
Applications
Show applications key
Our Abpromise guarantee covers the use of ab10164 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
Target
Function
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Involvement in disease
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
Sequence similarities
Belongs to the peroxidase family. XPO subfamily.
Cellular localization
Lysosome.
Target information above from: UniProt accessionP05164
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
Database links
- Entrez Gene: 4353 Human
- Omim: 606989 Human
- SwissProt: P05164 Human
- Unigene: 458272 Human
References for Anti-Myeloperoxidase antibody [2A11] (ab10164)
ab10164 has not yet been referenced specifically in any publications.
Publishing research using ab10164? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"