|
|
|
|
|
Product Name
|
MyoD1 antibody [5.2F], prediluted
|
| |
See all MyoD1 antibodies (9)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Mouse monoclonal [5.2F] to MyoD1, prediluted
|
|
Immunogen
|
BALB/C mice were injected with a recombinant mouse MyoD1 protein.
|
|
Reacts with
(species key)
|
Ms
|
|
Specificity
|
This antibody is specific to a 45 kD protein. This antibody does not react with myogenin, Myf5 or Myf6.
MyoD1 stains the nuclei of myoblasts in developing muscle tissues.
MyoD1 is not detected in normal adult tissue but is expressed strongly in the tumor cell nuclei of rhabdomyosarcomas.
|
|
Epitope
|
This antibody is specific to an epitope of amino acid 3-56 in the N-terminus of mouse MyoD1.
|
|
Tested applications
(see key)
|
IHC-Fr
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
IHC-Fr: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
Tonsil
|
|
Cellular localization
|
Nuclear
|
|
Research areas
|
Developmental Biology >> Organogenesis >> Skeletal development >> Muscle
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
|
|
Relevance
|
MyoD1 belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. Myod1 is essential for repair of damaged tissue. It activates its own transcription which may stabilize commitment to myogenesis.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window Entrez Gene | | 17927 (Mouse)
|
| |
|
|
Raised in
|
Mouse
|
|
Clonality
|
Monoclonal
|
|
Clone number
|
5.2F
|
|
Isotype
|
IgG2a
|
|
Purity
|
Protein A purified
|
|
Storage buffer
|
Preservative: Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
|
|
Form
|
Liquid
|
|
Storage instructions
|
Store at +4°C.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MyoD1 antibody [5.2F], prediluted is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to MyoD1
|
| |
MyoD1 antibody [5.2F], prediluted - more information
|
Customer reviews (feedback) regarding MyoD1 antibody [5.2F], prediluted |
Customer FAQs regarding MyoD1 antibody [5.2F], prediluted |
Protocols for MyoD1 antibody [5.2F], prediluted |
Price and availability of products related to MyoD1 antibody [5.2F], prediluted |
| |
MyoD1 antibody [5.2F], prediluted - related products:
|
|
|
| |
MyoD1 antibody [5.2F], prediluted - other tools:
|
Contact Abcam with a Technical Enquiry about MyoD1 antibody [5.2F], prediluted |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
