Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Cadherins
Overview
Product name
Anti-N Cadherin antibody [NC-17]
See all N Cadherin products (19) ...
Description
Mouse monoclonal [NC-17] to N Cadherin
Tested applications
WB, IHC-Frmore details
Cross reactivity
Reacts with
Mouse, Rat, Rabbit, Chicken, Human
Immunogen
Affinity purified chicken heart N Cadherin.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 1.2% Sodium acetate, 2mg/ml BSA
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
NC-17
Isotype
IgG1
Research areas
Cancer >> Invasion/microenvironment >> ECM >> Cell adhesion >> Cadherins
Stem Cells >> Hematopoietic Progenitors >> Surface Molecules
Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Cadherins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab82256 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 2 µg/mlPredicted molecular weight: 100 kDa.
IHC-Fr: Use a concentration of 4 µg/ml(Formalin or acetone fixed tissues.)
Application notes
Is unsuitable for or IHC-P.
Target
Function
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
Sequence similarities
Contains 5 cadherin domains.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionP19022
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- CADH2_HUMAN antibody
- Cadherin 2 antibody
- Cadherin 2 N cadherin neuronal antibody
see all
Database links
- Entrez Gene: 414745 Chicken
- Entrez Gene: 1000 Human
- Entrez Gene: 12558 Mouse
- Entrez Gene: 83501 Rat
- Omim: 114020 Human
- SwissProt: P10288 Chicken
- SwissProt: P19022 Human
- SwissProt: P15116 Mouse
see all
References for Anti-N Cadherin antibody [NC-17] (ab82256)
ab82256 has not yet been referenced specifically in any publications.
Publishing research using ab82256? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"