N-Desmethyl clozapine (Normethylclozapine) (ab120026)
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
References for N-Desmethyl clozapine (Normethylclozapine) (ab120026)
This product has been referenced in:
- Burstein ES et al. Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist. J Pharmacol Exp Ther 315:1278-87 (2005). Read more (PubMed: 16135699) »
- Sur C et al. N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity. Proc Natl Acad Sci U S A 100:13674-9 (2003). Read more (PubMed: 14595031) »
- Fox S & Brotchie J Normethylclozapine potentiates the action of quinpirole in the 6-hydroxydopamine lesioned rat. Eur J Pharmacol 301:27-30 (1996). Read more (PubMed: 8773443) »