![Western blot - NAB1 antibody [2607C2a] (ab58884) image](#ab58884.gif)
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Products:Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Overview
Product name
Anti-NAB1 antibody [2607C2a]
See all NAB1 products (3) ...
Description
Mouse monoclonal [2607C2a] to NAB1
Tested applications
Dot Blot, WBmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment (Human)
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS (8.0mM Sodium phosphate, 3.0mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate), pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
Purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
Clonality
Monoclonal
Clone number
2607C2a
Isotype
IgG1
Research areas
Cardiovascular >> Heart >> Hypertrophy >> Transcription factors
Epigenetics and Nuclear Signaling >> Transcription >> Co-factors
Epigenetics and Nuclear Signaling >> Transcription >> Other factors
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Western blot - NAB1 antibody [2607C2a] (ab58884)
![Western blot - NAB1 antibody [2607C2a] (ab58884) image](/ps/datasheet/Images/58/ab58884/ab58884.gif)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab58884 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Dot: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 54 kDa.
Target
Function
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2.
Tissue specificity
Isoform Short is found in a myeloid leukemia cell line.
Sequence similarities
Belongs to the NAB family.
Domain
The NAB conserved domain 1 (NCD1) interacts with EGR1 inhibitory domain and mediates multimerization.
The NAB conserved domain 2 (NCD2) is necessary for transcriptional repression.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ13506
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- EGR 1 binding protein 1 antibody
- EGR-1-binding protein 1 antibody
- NAB1 antibody
see all
Database links
- Entrez Gene: 4664 Human
- Omim: 600800 Human
- SwissProt: Q13506 Human
- Unigene: 723892 Human
Anti-NAB1 antibody [2607C2a] images:
Western blot - NAB1 antibody [2607C2a] (ab58884)
Anti-NAB1 antibody [2607C2a] (ab58884) + immunizing recombinant fragment
Predicted band size : 54 kDa
The molecular weight of the band on the western blot does not correspond to the molecular weight of the natural protein because only a fragment of the protein was used.
References for Anti-NAB1 antibody [2607C2a] (ab58884)
ab58884 has not yet been referenced specifically in any publications.
Publishing research using ab58884? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"