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NAIP peptide (ab39795)

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Overview

Product name

NAIP peptide

Protein description

NAIP (C-Terminus) Peptide (Human)

Properties

Purification notes

ab39795 is a crude synthetic peptide, purity range from 60-70%. The sequence is proprietary.

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS, pH 7.2

Concentration

Concentration information loading...

Research areas

Cancer >> Invasion/microenvironment >> Apoptosis >> Death receptors & ligands >> IAPs
Cell Biology >> Apoptosis >> Intracellular >> Survivin / IAPs

Applications

Show applications key

Our Abpromise guarantee covers the use of ab39795 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    WB

     WB: Use at an assay depe...Read more →

    WB: Use at an assay dependent dilution. Predicted molecular weight: 160 kDa.

Application notes

This peptide can be used with studies using ab25968.

Protein info

Function

Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.

Tissue specificity

Expressed in motor neurons, but not in sensory neurons. Found in liver and placenta, and to a lesser extent in spinal cord.

Sequence similarities

Contains 3 BIR repeats.
Contains 1 NACHT domain.

Target information above from: UniProt accessionQ13075 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for NAIP peptide (ab39795)

ab39795 has not yet been referenced specifically in any publications.

Publishing research using ab39795? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"