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Products:Signal Transduction >> Metabolism >> Drug metabolism
Overview
Product name
Anti-NAT2 antibody
See all NAT2 products (5) ...
Description
Mouse monoclonal to NAT2
Tested applications
Cross reactivity
Reacts with
Recombinant Fragment
Predicted to work with
Human
Immunogen
Recombinant fragment: PPVNKYSTGM VHLLLQVTID GRNYIVDAGS GSSSQMWQPL ELISGKDQPQ VPCIFCLTEE RGIWYLDQIR REQYITNKEF LNSHLLPKKK HQKIYLFTLE , corresponding to amino acids 96-195 of Human NAT2
PPVNKYSTGM VHLLLQVTID GRNYIVDAGS GSSSQMWQPL ELISGKDQPQ VPCIFCLTEE RGIWYLDQIR REQYITNKEF LNSHLLPKKK HQKIYLFTLE
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
-
Western blot - NAT2 antibody (ab54691)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab54691 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
Sequence similarities
Belongs to the arylamine N-acetyltransferase family.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionP11245
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AAC2 antibody
- ARY2_HUMAN antibody
- Arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation) antibody
see all
Database links
- Entrez Gene: 10 Human
- Omim: 243400 Human
- SwissProt: P11245 Human
- Unigene: 2 Human
Anti-NAT2 antibody images:
Western blot - NAT2 antibody (ab54691)
Western blot against tagged recombinant protein immunogen using ab54691 NAT2 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
References for Anti-NAT2 antibody (ab54691)
ab54691 has not yet been referenced specifically in any publications.
Publishing research using ab54691? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"