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Products:Signal Transduction >> Metabolism >> Drug metabolism
Overview
Product name
Anti-NAT2 antibody
See all NAT2 products (5) ...
Description
Mouse polyclonal to NAT2
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length human NAT2 protein (AAH15878.1).
Positive control
NAT2 transfected 293T cell lysate, human liver tissue lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Applications
Show applications key
Our Abpromise guarantee covers the use of ab88443 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 µg/mlPredicted molecular weight: 34 kDa.
Target
Function
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
Sequence similarities
Belongs to the arylamine N-acetyltransferase family.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionP11245
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AAC2 antibody
- ARY2_HUMAN antibody
- Arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation) antibody
see all
Database links
- Entrez Gene: 10 Human
- Omim: 243400 Human
- SwissProt: P11245 Human
- Unigene: 2 Human
Anti-NAT2 antibody images:
Western blot - NAT2 antibody (ab88443)
Anti-NAT2 antibody (ab88443) at 1 µg/ml + human liver tissue lysate at 50 µg
Predicted band size : 34 kDa
Observed band size : 30 kDa (why is the actual band size different from the predicted?)
Western blot - NAT2 antibody (ab88443)
All lanes : Anti-NAT2 antibody (ab88443) at 1 µg/ml
Lane 1 : NAT2 transfected 293T cell lysate
Lane 2 : non transfected 293T cell lysate
Lysates/proteins at 50 µg per lane.
Predicted band size : 34 kDa
Observed band size : 34 kDa
References for Anti-NAT2 antibody (ab88443)
ab88443 has not yet been referenced specifically in any publications.
Publishing research using ab88443? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"