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Anti-NDUFB6 antibody (ab110244)

MSCatalog No. MS108

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Overview

Product name

Anti-NDUFB6 antibody
See all NDUFB6 products (3) ...

Description

Mouse monoclonal to NDUFB6

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Cow, Human

Immunogen

NDUFB6 from cow

Positive control

Isolated mitochondria from Human heart, bovine heart, rat heart and mouse heart.

Properties

Form

Liquid

Storage instructions

Store at +4°C. Do not freeze.

Storage buffer

Preservative: 0.02% Sodium azide
Constituent: HBS

Concentration

Concentration information loading...

Purification notes

Near homogeneity as judged by SDS-PAGE. The antibody was produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.

Clonality

Monoclonal

Isotype

IgG2b

Light chain type

kappa

Research areas

Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Mitochondrial Metabolism >> Oxidative phosphorylation >> Complex I
Metabolism >> Pathways and Processes >> Redox metabolism >> Oxidative stress
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Energy transfer pathways >> Integration of energy
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Energy transfer pathways >> Energy Metabolism
Metabolism >> Pathways and Processes >> Mitochondrial Metabolism >> Mitochondrial markers
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Integration of energy metabolism
Cell Biology >> Other Antibodies >> Oxidative Stress
Signal Transduction >> Metabolism >> Mitochondrial
Signal Transduction >> Metabolism >> Energy Metabolism

  • Western blot - Anti-NDUFB6 antibody (ab110244)Western blot - Anti-NDUFB6 antibody (ab110244) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab110244 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Sequence similarities

Belongs to the complex I NDUFB6 subunit family.

Cellular localization

Mitochondrion inner membrane.

Target information above from: UniProt accessionO95139 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • B17 antibody
  • CI antibody
  • CI B17 antibody
  • CI-B17 antibody
  • Complex I mitochondrial respiratory chain B17 subunit antibody
  • Complex I-B17 antibody
  • Complex IB17 antibody
  • MGC13675 antibody
  • MS108 antibody
  • NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6 antibody
  • NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 antibody
  • NADH ubiquinone oxidoreductase B17 subunit antibody
  • NADH ubiquinone oxidoreductase beta subunit 6 antibody
  • NADH-ubiquinone oxidoreductase B17 subunit antibody
  • NDUB6_HUMAN antibody
  • NDUFB6 antibody
see all

Database links

Anti-NDUFB6 antibody images:

  Western blot - Anti-NDUFB6 antibody (ab110244)

Western blot - Anti-NDUFB6 antibody (ab110244)

All lanes : Anti-NDUFB6 antibody (ab110244) at 0.5 µg/ml

Lane 1 : isolated mitochondria from Human heart at 5 µg
Lane 2 : isolated mitochondria from cow heart at 1 µg
Lane 3 : isolated mitochondria from rat heart at 10 µg
Lane 4 : isolated mitochondria from mouse heart at 10 µg


Predicted band size : 15 kDa

References for Anti-NDUFB6 antibody (ab110244)

This product has been referenced in:

  • Rardin MJ  et al. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem 283:15440-50 (2008).Read more (PubMed: 18385140) »
  • Ling C  et al. Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle. J Clin Invest 117:3427-35 (2007).Read more (PubMed: 17948130) »

See all 12 publications for this product

Publishing research using ab110244? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"