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Read our guarantee »Products:Epigenetics and Nuclear Signaling >> Transcription >> Elongation factors
Anti-NELFe antibody
See all NELFe products (2) ...
Rabbit polyclonal to NELFe
IHC-Pmore details
Reacts with
Human
Synthetic peptide, corresponding to a region between residue 330 and 380 of human NELFe (NP_002895.3)
Human Breast Carcinoma, human Placenta
Liquid
Store at +4°C.
Preservative: 0.09% Sodium Azide
Constituents: 0.1% BSA, Tris buffered saline
Concentration information loading...
Immunogen affinity purified
Polyclonal
IgG
Epigenetics and Nuclear Signaling >> Transcription >> Elongation factors
Our Abpromise guarantee covers the use of ab84986 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/100 - 1/500.
Epitope exposure with citrate buffer will enhance staining.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas.
Belongs to the RRM NELF-E family.
Contains 1 RRM (RNA recognition motif) domain.
The RRM domain interacts with RNA, and is essential for NELF complex function. It is however not required for the NELF complex formation.
Sumoylated.
Nucleus.
Target information above from: UniProt accessionP18615
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NELFe antibody (ab84986)

ab84986 at 1/250 dilution staining NELFe in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NELFe antibody (ab84986)

ab84986 at 1/250 dilution staining NELFe in human placenta by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
ab84986 has not yet been referenced specifically in any publications.
Publishing research using ab84986? Please let us know so that we can cite the reference in this datasheet
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ab84986 at 1/250 dilution staining NELFe in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

ab84986 at 1/250 dilution staining NELFe in human placenta by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
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