Anti-NET1 antibody (ab79006)
Key features and details
- Goat polyclonal to NET1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NET1 antibody
See all NET1 primary antibodies -
Description
Goat polyclonal to NET1 -
Host species
Goat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chicken, Cow, Cynomolgus monkey, Orangutan -
Immunogen
Synthetic peptide:
DKLEYLDEKQRDPR,
Human, from the internal region of the protein sequence according to NP_005854.2; NP_001040625.1 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab79006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 2.5 µg/ml.
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Notes |
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IHC-P
Use a concentration of 2.5 µg/ml. |
Target
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Function
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. -
Tissue specificity
Widely expressed. -
Sequence similarities
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain. -
Cellular localization
Cytoplasm. Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 416693 Chicken
- Entrez Gene: 10276 Human
- Entrez Gene: 100173481 Orangutan
- SwissProt: Q7Z628 Human
- Unigene: 25155 Human
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Alternative names
- ARHG8_HUMAN antibody
- ARHGEF8 antibody
- GLYT2 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (1)
ab79006 has been referenced in 1 publication.
- Liang X et al. VTIQ evaluates antitumor effects of NET-1 siRNA by UTMD in HCC xenograft models. Oncol Lett 16:2893-2902 (2018). PubMed: 30127877