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Overview

  • Product nameNIR1 peptide (962-974)See all NIR1 proteins and peptides ...
  • Protein descriptionSynthetic peptide: C-SWARGPPKFESVP, corresponding to C terminal amino acids 962-974 of Human NIR1.

    This peptide was used as an immunogen for ab21197 - NIR1 antibody.

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Concentration information loading...
  • SequenceC-SWARGPPKFESVP
  • Research Areas

    • Protein info

    • Alternative names
        CORD5Membrane associated phosphatidylinositol transfer protein 3membrane-associated 3
        Membrane-associated phosphatidylinositol transfer protein 3MGC157740MGC157741NIR 1NIR-1NIR1Phosphatidylinositol transfer proteinPhosphatidylinositol transfer protein, membrane-associated 3PITM3_HUMANPITPNMPITPnm 3PITPNM family member 3Pitpnm3PYK2 N terminal domain interacting receptor 1PYK2 N-terminal domain-interacting receptor 1RDGBA3retinal degeneration B alpha 3
      see all
  • FunctionCatalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions.
  • Tissue specificityDetected in brain and spleen, and at low levels in ovary.
  • Involvement in diseaseDefects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) [MIM:600977]. CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.
  • Sequence similaritiesBelongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
    Contains 1 DDHD domain.
  • Cellular localizationEndomembrane system.

    • Target information above from: UniProt accession Q9BZ71 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for NIR1 peptide (962-974) (ab45573)

    ab45573 has not yet been referenced specifically in any publications.

    Publishing research using ab45573 ? Please let us know so that we can cite the reference in this datasheet

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