Overview

  • Product nameAnti-NIT1 antibodySee all NIT1 primary antibodies ...
  • Description
    Rabbit polyclonal to NIT1
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within N-terminal amino acids 71-120 (

    VREAARLGACLAFLPEAFDFIARDPAETLHLSEPLGGKLLEEYTQLAREC

    ) of Human NIT1 (NP_005591).

  • Positive control
    • 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab98066 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionPlay a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
  • Tissue specificityDetected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.
  • Sequence similaritiesBelongs to the UPF0012 family.
    Contains 1 CN hydrolase domain.
  • Cellular localizationCytoplasm. Mitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC57670 antibody
    • NIT1 antibody
    • NIT1_HUMAN antibody
    • Nitrilase 1 antibody
    • Nitrilase homolog 1 antibody
    see all

Anti-NIT1 antibody images

  • Anti-NIT1 antibody (ab98066) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T Cell Lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 36 kDa

References for Anti-NIT1 antibody (ab98066)

ab98066 has not yet been referenced specifically in any publications.

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