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Anti-NMDAR2B antibody [NR2B] (ab28373)

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Overview

Product name

Anti-NMDAR2B antibody [NR2B]
See all NMDAR2B products (18) ...

Description

Mouse monoclonal [NR2B] to NMDAR2B

Specificity

Detects the N-methyl-D-aspartate (NMDA) receptor type 2B. This antibody has been tested in mouse and rat brain in western blotting. It has not been tested in human for Western blotting - only for ICC on transfected HEK cells.

Tested applications

ICC, WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Recombinant fragment (Rat) - corresponding to amino acids 934 - 1457 of NR2B subunit.

Positive control

WB: Mouse brain tissue ICC: transfected HEK cells

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.05% Sodium Azide
Constituents: PBS, 1mg/ml BSA

Concentration

Concentration information loading...

Purity

Protein A purified

Purification notes

Protein A Chromatography

Clonality

Monoclonal

Clone number

NR2B

Isotype

IgG1

Research areas

Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Neuroscience >> Sensory System >> Somatosensory system >> Nociception
Neuroscience >> Neurotransmission >> Receptors / Channels >> Ligand-Gated Ion Channels >> NMDA Receptors

  • Western blot - NMDAR2B antibody [NR2B] (ab28373)Western blot - NMDAR2B antibody [NR2B] (ab28373) image (enlarge)

  • Western blot - NMDAR2B antibody [NR2B] (ab28373)Western blot - NMDAR2B antibody [NR2B] (ab28373) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab28373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

Tissue specificity

Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.

Sequence similarities

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily.

Cellular localization

Cell membrane. Cell junction > synapse > postsynaptic cell membrane.

Target information above from: UniProt accessionQ13224 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • AW490526 antibody
  • Glutamate [NMDA] receptor subunit epsilon 2 antibody
  • Glutamate [NMDA] receptor subunit epsilon-2 antibody
  • Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody
  • Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody
  • Glutamate receptor ionotropic NMDA2B antibody
  • Glutamate receptor subunit epsilon 2 antibody
  • Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody
  • GRIN 2B antibody
  • GRIN2B antibody
  • hNR 3 antibody
  • hNR3 antibody
  • MGC142178 antibody
  • MGC142180 antibody
  • N methyl D asparate receptor channel subunit epsilon 2 antibody
  • N METHYL D ASPARTATE RECEPTOR CHANNEL SUBUNIT EPSILON 2 antibody
  • N methyl D aspartate receptor subtype 2B antibody
  • N methyl D aspartate receptor subunit 2B antibody
  • N methyl D aspartate receptor subunit 3 antibody
  • N-methyl D-aspartate receptor subtype 2B antibody
  • N-methyl-D-aspartate receptor subunit 3 antibody
  • NMDA NR2B antibody
  • NMDA R2B antibody
  • Nmdar2b antibody
  • NMDE2 antibody
  • NMDE2_HUMAN antibody
  • NME2 antibody
  • NR2B antibody
  • NR3 antibody
see all

Database links

see all

Anti-NMDAR2B antibody [NR2B] images:

  Western blot - NMDAR2B antibody [NR2B] (ab28373)

Western blot - NMDAR2B antibody [NR2B] (ab28373)

Anti-NMDAR2B antibody [NR2B] (ab28373) at 2 µg/ml + mouse brain tissue

Predicted band size : 166 kDa

  Western blot - NMDAR2B antibody [NR2B] (ab28373)

Western blot - NMDAR2B antibody [NR2B] (ab28373)

Lanes 2 - 4 : Anti-NMDAR2B antibody [NR2B] (ab28373) at 1/500 dilution
Lanes 5 - 7 : Anti-NMDAR2B antibody [NR2B] (ab28373) at 1/1000 dilution

Lane 2 : As above
Lane 3 : Mouse brain (50ug)
Lane 4 : Rat brain (50ug)
Lane 5 : As above
Lane 6 : Mouse brain (50ug)
Lane 7 : Rat brain (50ug)


Predicted band size : 166 kDa

References for Anti-NMDAR2B antibody [NR2B] (ab28373)

ab28373 has not yet been referenced specifically in any publications.

Publishing research using ab28373? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"