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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NOMO1 antibody (ab79988)
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Product Name
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NOMO1 antibody
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See all NOMO1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to NOMO1
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Immunogen
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KLH conjugated synthetic peptide selected from the C terminal region of human NOMO1.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ELISA, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/1000.
IHC-P: 1/10 - 1/50.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human colon carcinoma tissue
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Cellular localization
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Membrane; Single pass type I membrane protein
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Research areas
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Developmental Biology >> Embryogenesis >> Axis formation and symmetry
Signal Transduction >> Growth Factors/Hormones >> TGF
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Relevance
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NOMO1 originally thought to be related to the collagenase family. There are 3 copies of the NOMO gene on chromosome 16p12-p13: NOMO1, NOMO2 and NOMO3. All encode very similar proteins which may have the same function. Most experiments probably do not discriminate between these different members, which are collectively referred to as 'NOMO'.
NOMO acts as an antagonist of the Nodal signaling pathway which is involved in very early in vertebrate embryogenesis. Mutations in ABCC6, which is located nearby, rather than mutations in NOMO are associated with pseudoxanthoma elasticum (PXE).
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.09% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Form
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Liquid
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Concentration
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0.250 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this NOMO1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for NOMO1 antibody images, references, products related to ab79988 and other tools.
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NOMO1 antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NOMO1 antibody (ab79988)
ab79988, at a 1/10 dilution, staining NOMO1 in formalin fixed, paraffin embedded human colon carcinoma tissue by Immunohistochemistry. ab79988 was peroxidase conjugated to the secondary antibody, followed by DAB staining.
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Search PubMed (MEDLINE) for references to NOMO1
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NOMO1 antibody - more information
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Customer reviews (feedback) regarding NOMO1 antibody |
Customer FAQs regarding NOMO1 antibody |
Protocols for NOMO1 antibody |
Price and availability of products related to NOMO1 antibody |
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NOMO1 antibody - related products:
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NOMO1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about NOMO1 antibody |
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