Anti-NPY1R antibody - Cytoplasmic domain (ab219266)
Key features and details
- Rabbit polyclonal to NPY1R - Cytoplasmic domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NPY1R antibody - Cytoplasmic domain
See all NPY1R primary antibodies -
Description
Rabbit polyclonal to NPY1R - Cytoplasmic domain -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except NPY6R (61%). -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat, Sheep, Rabbit, Horse, Guinea pig, Hamster, Dog, Pig, Monkey, Bat -
Immunogen
Synthetic peptide within Human NPY1R. The exact sequence is proprietary. 18 amino acid peptide from 3rd cytoplasmic domain of Human NPY1R.
Database link: P25929 -
Positive control
- IHC-P; Human Skin (Melanoma) tissue and Human brain tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.099% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab219266 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 16 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 16 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 4886 Human
- Entrez Gene: 397547 Pig
- Entrez Gene: 29358 Rat
- Omim: 162641 Human
- SwissProt: O02813 Dog
- SwissProt: Q9WVD0 Guinea pig
- SwissProt: P25929 Human
- SwissProt: O02835 Pig
see all -
Alternative names
- Neuropeptide Y receptor type 1 antibody
- Neuropeptide Y receptor Y1 antibody
- NPY1-R antibody
see all
Images
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin (Melanoma) tissue labeling NPY1R with ab219266 at 16 µg/ml.
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin (Melanoma) tissue labeling NPY1R with ab219266 at 16 µg/ml.
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling NPY1R with ab219266 at 16 µg/ml.
Datasheets and documents
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Datasheet download
References (0)
ab219266 has not yet been referenced specifically in any publications.