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Products:Signal Transduction >> Metabolism >> Drug metabolism
Overview
Product name
Anti-NQO1 antibody
See all NQO1 products (11) ...
Description
Rabbit polyclonal to NQO1
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
KLH conjugated synthetic peptide selected from an internal region of Human NQO1 (NP_000894).
Positive control
NCI-H460 cell line lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Ammonium Sulphate Precipitation
Purification notes
ab85253 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
IgG
Research areas
-
Western blot - NQO1 antibody (ab85253)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab85253 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/50 - 1/100.Predicted molecular weight: 31 kDa.
ELISA
ELISA: 1/1000ELISA: 1/1000
Target
Function
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Sequence similarities
Belongs to the NAD(P)H dehydrogenase (quinone) family.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionP15559
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Azoreductase antibody
- Menadione reductase antibody
- Phylloquinone reductase antibody
see all
Database links
- Entrez Gene: 1728 Human
- Omim: 125860 Human
- SwissProt: P15559 Human
- Unigene: 406515 Human
Anti-NQO1 antibody images:
Western blot - NQO1 antibody (ab85253)
Anti-NQO1 antibody (ab85253) at 1/50 dilution + NCI-H460 cell line lysate at 35 µg
Predicted band size : 31 kDa
Observed band size : 31 kDa
References for Anti-NQO1 antibody (ab85253)
ab85253 has not yet been referenced specifically in any publications.
Publishing research using ab85253? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"