Anti-NR2E1 / Tailless antibody (ab82667)

Overview

• Product nameAnti-NR2E1 / Tailless antibodySee all NR2E1 / Tailless primary antibodies ...
• Description
  Rabbit polyclonal to NR2E1 / Tailless
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Dog, Zebrafish
• Immunogen

  Synthetic peptide from within internal sequence amino acids 143-192 (LAAVSTTPER QTLVSLAQPT PKYPHEVNGT PMYLYEVATE SVCESAARLL) of NR2E1 / Tailless (NP_003260)

  Run BLAST with Run BLAST with
• Positive controlHepG2 cell lysate

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: 2% Sucrose, PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Stem Cells
  • Neural Stem Cells
  • Intracellular

  • Signal Transduction
  • Signaling Pathway
  • Nuclear Signaling
  • Nuclear Hormone Receptors
  • Corticoid

  • Epigenetics and Nuclear Signaling
  • Nuclear Signaling Pathways
  • Nuclear Receptors
  • Corticoid

  • Neuroscience
  • Cell Type Marker
  • Neural Stem Cell marker

Applications

Target

• FunctionOrphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development.
• Tissue specificityBrain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus.
• Sequence similaritiesBelongs to the nuclear hormone receptor family. NR2 subfamily.
  Contains 1 nuclear receptor DNA-binding domain.
• Cellular localizationNucleus.

Target information above from: UniProt accession Q9Y466 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 7101 Human
  • Entrez Gene: 21907 Mouse
  • Entrez Gene: 684085 Rat
  • Entrez Gene: 445214 Zebrafish
  • Omim: 603849 Human
  • SwissProt: Q9Y466 Human
  • SwissProt: Q3UXE8 Mouse
  • SwissProt: Q78ZM1 Mouse

  • SwissProt: Q64104 Mouse
  • SwissProt: Q6DEH0 Zebrafish
  • Unigene: 157688 Human
  • Unigene: 287100 Mouse

  see all

• Alternative names
  hTll antibodynr2e1 antibodyNR2E1_HUMAN antibody

  Nuclear receptor subfamily 2 group E member 1 antibodyNuclear receptor TLX antibodyOrphan nuclear receptor NR2E1 antibodyProtein tailless homolog antibodyTailless homolog antibodyTll antibodyTLX antibodyXTLL antibody

  see all

Anti-NR2E1 / Tailless antibody images

• 

  Western blot - NR2E1 / Tailless antibody (ab82667)
  Anti-NR2E1 / Tailless antibody (ab82667) at 1 µg/ml (5% skim milk/ PBS buffer) + HepG2 cell lysate at 10 µg with gel concentration: 12%
  
  Secondary
  HRP conjugated anti-Rabbit IgG at 1/50000 dilution
  
  Predicted band size : 43 kDa
  Observed band size : 42 kDa (why is the actual band size different from the predicted?)