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NRG1 type III peptide (ab23378)

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Overview

Product name

NRG1 type III peptide

Protein description

Synthetic peptide derived from within residues 50 - 150 of Human NRG1 type III. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab23248.

Protein length

296 amino acids

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Information available upon request.

Concentration

Concentration information loading...

Research areas

Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Growth and Development >> Axonal Guidance Proteins
Neuroscience >> Neurology process >> Neural Signal Transduction

Applications

Application notes

This peptide can be used with studies using ab23248.

Protein info

Relevance

NRG1 type III is a sensory and motor neuron-derived factor isoform of Neuregulin 1, specifically expressed in the nervous system: spinal cord motor neurons, dorsal root ganglion neurons, and brain. NRG1 type III is the predominant isoform expressed in sensory and motor neurons. The Nrg1 gene encodes more than 15 transmembrane and secreted protein isoforms, generated by alternative promoter usage and mRNA splicing. Nrg1 subtypes I through III share the epidermal growth factor-like signaling domain and are defined by different amino-termini. The N-terminal cysteine-rich domain (CRD), as found in the sensory and motor neuronderived factor (SMDF), defines Nrg1 type III, which in embryonic development is responsible for survival of Schwann cell precursors.

Cellular localization

Cell Membrane and Secreted

References for NRG1 type III peptide (ab23378)

ab23378 has not yet been referenced specifically in any publications.

Publishing research using ab23378? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"