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Product Name
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NXF1 peptide
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Product type
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Proteins and Peptides
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Peptide
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Synthetic peptide derived from within residues 150 - 250 of Human NXF1.This peptide was used as an immunogen for ab43421 - NXF1 antibody.
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Research areas
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Tags & Cell Markers >> Subcellular Markers >> Nucleus >> Nucleoplasm
Tags & Cell Markers >> Subcellular Markers >> Nucleus >> Nuclear Pore
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Relevance
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NXF1 (Nuclear Export Factor 1)is a 70 kDa protein involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and is thought to be a principal export receptor for cellular mRNA, from the nucleus to the cytoplasm. NXF1 is primarily located in the nucleoplasm but it can also be found in association with both the cytoplasmic and the nucleoplasmic ends of the nuclear pore complex. It contains an N-terminal nuclear localization and export region (NLS-NES), a central RNA binding domain (RBD), and a C-terminal portion that is required for nuclear localization and nuclear rim association. It is expressed ubiquitously.
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Storage buffer
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Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this NXF1 peptide is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to NXF1
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